diff --git a/pkgs/development/python-modules/mlflow/default.nix b/pkgs/development/python-modules/mlflow/default.nix
index 9b0f8e2538e6..1bed42479c8a 100644
--- a/pkgs/development/python-modules/mlflow/default.nix
+++ b/pkgs/development/python-modules/mlflow/default.nix
@@ -6,11 +6,11 @@
 , databricks-cli
 , docker
 , entrypoints
-, fetchpatch
 , fetchPypi
 , flask
 , gitpython
 , gorilla
+, graphene
 , gunicorn
 , importlib-metadata
 , markdown
@@ -28,9 +28,9 @@
 , pyyaml
 , querystring-parser
 , requests
+, setuptools
 , scikit-learn
 , scipy
-, shap
 , simplejson
 , sqlalchemy
 , sqlparse
@@ -39,24 +39,22 @@
 buildPythonPackage rec {
   pname = "mlflow";
   version = "2.11.1";
-  format = "setuptools";
+  pyproject = true;
 
-  disabled = pythonOlder "3.7";
+  disabled = pythonOlder "3.8";
 
   src = fetchPypi {
     inherit pname version;
     hash = "sha256-ouwp7oYvGZVSCPuOBeUeXp0u3HF143zxNtlDuYGoJOk=";
   };
 
-  postPatch = ''
-    substituteInPlace requirements/core-requirements.txt \
-      --replace "gunicorn<21" "gunicorn"
-  '';
-
   # Remove currently broken dependency `shap`, a model explainability package.
   # This seems quite unprincipled especially with tests not being enabled,
   # but not mlflow has a 'skinny' install option which does not require `shap`.
-  nativeBuildInputs = [ pythonRelaxDepsHook ];
+  nativeBuildInputs = [
+    pythonRelaxDepsHook
+    setuptools
+  ];
   pythonRemoveDeps = [ "shap" ];
   pythonRelaxDeps = [ "pytz" "pyarrow" ];
 
@@ -70,6 +68,7 @@ buildPythonPackage rec {
     flask
     gitpython
     gorilla
+    graphene
     gunicorn
     importlib-metadata
     markdown