diff --git a/pkgs/applications/virtualization/xen/4.10.nix b/pkgs/applications/virtualization/xen/4.10.nix
index c3280cbda94b..dab90a1ed781 100644
--- a/pkgs/applications/virtualization/xen/4.10.nix
+++ b/pkgs/applications/virtualization/xen/4.10.nix
@@ -29,6 +29,12 @@ let
 
   xsa = import ./xsa-patches.nix { inherit fetchpatch; };
 
+  qemuMemfdBuildFix = fetchpatch {
+    name = "xen-4.8-memfd-build-fix.patch";
+    url = https://github.com/qemu/qemu/commit/75e5b70e6b5dcc4f2219992d7cffa462aa406af0.patch;
+    sha256 = "0gaz93kb33qc0jx6iphvny0yrd17i8zhcl3a9ky5ylc2idz0wiwa";
+  };
+
   qemuDeps = [
     udev pciutils xorg.libX11 SDL pixman acl glusterfs spice-protocol usbredir
     alsaLib glib python2
@@ -53,6 +59,9 @@ callPackage (import ./generic.nix (rec {
         rev = "b79708a8ed1b3d18bee67baeaf33b3fa529493e2";
         sha256 = "1yxxad6nvlfmrbgyc8ix19qmrsn1rx4zpyiqnfi4x4kg94acwa5w";
       };
+      patches = [
+        qemuMemfdBuildFix
+      ];
       buildInputs = qemuDeps;
       postPatch = ''
         # needed in build but /usr/bin/env is not available in sandbox