diff --git a/pkgs/development/python-modules/bootstrapped-pip/default.nix b/pkgs/development/python-modules/bootstrapped-pip/default.nix
index 5578b3a83c4d..677736270290 100644
--- a/pkgs/development/python-modules/bootstrapped-pip/default.nix
+++ b/pkgs/development/python-modules/bootstrapped-pip/default.nix
@@ -25,15 +25,19 @@ in stdenv.mkDerivation rec {
     unzip -d $out/${python.sitePackages} ${wheel_source}
   '';
 
-  buildInputs = [ python makeWrapper unzip ];
-
-  installPhase = ''
+  patchPhase = ''
     mkdir -p $out/bin
 
     # patch pip to support "pip install --prefix"
+    # https://github.com/pypa/pip/pull/3252
     pushd $out/${python.sitePackages}/
     patch -p1 < ${./pip-7.0.1-prefix.patch}
     popd
+  '';
+
+  buildInputs = [ python makeWrapper unzip ];
+
+  installPhase = ''
 
     # install pip binary
     echo '${python.interpreter} -m pip "$@"' > $out/bin/pip
diff --git a/pkgs/development/python-modules/generic/default.nix b/pkgs/development/python-modules/generic/default.nix
index 75115526a41e..0a2fd429f002 100644
--- a/pkgs/development/python-modules/generic/default.nix
+++ b/pkgs/development/python-modules/generic/default.nix
@@ -50,7 +50,7 @@ then throw "${name} not supported for interpreter ${python.executable}"
 else
 
 let
-  setuppy = "import setuptools, tokenize;__file__='setup.py';exec(compile(getattr(tokenize, 'open', open)(__file__).read().replace('\\r\\n', '\\n'), __file__, 'exec'))";
+  setuppy = ./run_setup.py;
 in
 python.stdenv.mkDerivation (builtins.removeAttrs attrs ["disabled"] // {
   inherit doCheck;
@@ -75,18 +75,19 @@ python.stdenv.mkDerivation (builtins.removeAttrs attrs ["disabled"] // {
     runHook postConfigure
   '';
 
-  checkPhase = attrs.checkPhase or ''
-    runHook preCheck
-    ${python.interpreter} -c "${setuppy}" test
-    runHook postCheck
-  '';
-
   buildPhase = attrs.buildPhase or ''
     runHook preBuild
-    ${python.interpreter} -c "${setuppy}" bdist_wheel
+    cp ${setuppy} nix_run_setup.py
+    ${python.interpreter} nix_run_setup.py build_ext ${lib.concatStringsSep " " setupPyBuildFlags} bdist_wheel
     runHook postBuild
   '';
 
+  checkPhase = attrs.checkPhase or ''
+    runHook preCheck
+    ${python.interpreter} nix_run_setup.py test
+    runHook postCheck
+  '';
+
   installPhase = attrs.installPhase or ''
     runHook preInstall
 
diff --git a/pkgs/development/python-modules/generic/run_setup.py b/pkgs/development/python-modules/generic/run_setup.py
new file mode 100644
index 000000000000..d980ac7d23d4
--- /dev/null
+++ b/pkgs/development/python-modules/generic/run_setup.py
@@ -0,0 +1,6 @@
+import setuptools
+import tokenize
+
+__file__='setup.py';
+
+exec(compile(getattr(tokenize, 'open', open)(__file__).read().replace('\\r\\n', '\\n'), __file__, 'exec'))