diff --git a/pkgs/applications/blockchains/monero-gui/default.nix b/pkgs/applications/blockchains/monero-gui/default.nix
index 48a6d81b6ba1..cfd3998ee368 100644
--- a/pkgs/applications/blockchains/monero-gui/default.nix
+++ b/pkgs/applications/blockchains/monero-gui/default.nix
@@ -5,7 +5,7 @@
 , qtquickcontrols, qtquickcontrols2
 , monero, unbound, readline, boost, libunwind
 , libsodium, pcsclite, zeromq, cppzmq
-, hidapi, libusb, protobuf, randomx
+, hidapi, libusb-compat-0_1, protobuf, randomx
 }:
 
 with stdenv.lib;
@@ -29,7 +29,7 @@ stdenv.mkDerivation rec {
     qtxmlpatterns
     monero unbound readline
     boost libunwind libsodium pcsclite zeromq
-    cppzmq hidapi libusb protobuf randomx
+    cppzmq hidapi libusb-compat-0_1 protobuf randomx
   ];
 
   NIX_CFLAGS_COMPILE = [ "-Wno-error=format-security" ];
diff --git a/pkgs/applications/blockchains/monero/default.nix b/pkgs/applications/blockchains/monero/default.nix
index 2a04beb93796..d1abd3956570 100644
--- a/pkgs/applications/blockchains/monero/default.nix
+++ b/pkgs/applications/blockchains/monero/default.nix
@@ -2,7 +2,7 @@
 , cmake, pkgconfig
 , boost, miniupnpc, openssl, unbound, cppzmq
 , zeromq, pcsclite, readline, libsodium, hidapi
-, pythonProtobuf, randomx, rapidjson, libusb
+, pythonProtobuf, randomx, rapidjson, libusb-compat-0_1
 , CoreData, IOKit, PCSC
 }:
 
@@ -26,7 +26,7 @@ stdenv.mkDerivation rec {
     boost miniupnpc openssl unbound
     cppzmq zeromq pcsclite readline
     libsodium hidapi randomx rapidjson
-    pythonProtobuf libusb
+    pythonProtobuf libusb-compat-0_1
   ] ++ stdenv.lib.optionals stdenv.isDarwin [ IOKit CoreData PCSC ];
 
   cmakeFlags = [
diff --git a/pkgs/applications/graphics/sane/backends/brscan4/default.nix b/pkgs/applications/graphics/sane/backends/brscan4/default.nix
index 22e8a2ca5360..2ada41ac98a1 100644
--- a/pkgs/applications/graphics/sane/backends/brscan4/default.nix
+++ b/pkgs/applications/graphics/sane/backends/brscan4/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, callPackage, patchelf, makeWrapper, coreutils, libusb }:
+{ stdenv, fetchurl, callPackage, patchelf, makeWrapper, coreutils, libusb-compat-0_1 }:
 
 let
   myPatchElf = file: with stdenv.lib; ''
@@ -30,13 +30,13 @@ in stdenv.mkDerivation rec {
   '';
 
   nativeBuildInputs = [ makeWrapper patchelf coreutils udevRules ];
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
   dontBuild = true;
 
   patchPhase = ''
     ${myPatchElf "opt/brother/scanner/brscan4/brsaneconfig4"}
 
-    RPATH=${libusb.out}/lib
+    RPATH=${libusb-compat-0_1.out}/lib
     for a in usr/lib64/sane/*.so*; do
       if ! test -L $a; then
         patchelf --set-rpath $RPATH $a
diff --git a/pkgs/applications/graphics/sane/frontends.nix b/pkgs/applications/graphics/sane/frontends.nix
index 188431bda6c6..885dff311b8f 100644
--- a/pkgs/applications/graphics/sane/frontends.nix
+++ b/pkgs/applications/graphics/sane/frontends.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, sane-backends, libX11, gtk2, pkgconfig, libusb ? null }:
+{ stdenv, fetchurl, sane-backends, libX11, gtk2, pkgconfig, libusb-compat-0_1 ? null }:
 
 stdenv.mkDerivation rec {
   pname = "sane-frontends";
@@ -14,7 +14,7 @@ stdenv.mkDerivation rec {
   '';
 
   buildInputs = [ sane-backends libX11 gtk2 ]
-    ++ stdenv.lib.optional (libusb != null) libusb;
+    ++ stdenv.lib.optional (libusb-compat-0_1 != null) libusb-compat-0_1;
   nativeBuildInputs = [ pkgconfig ];
 
   enableParallelBuilding = true;
diff --git a/pkgs/applications/graphics/sane/xsane.nix b/pkgs/applications/graphics/sane/xsane.nix
index 22a8f4dc3bda..04d19dee8a8e 100644
--- a/pkgs/applications/graphics/sane/xsane.nix
+++ b/pkgs/applications/graphics/sane/xsane.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchurl, sane-backends, sane-frontends, libX11, gtk2, pkgconfig, libpng
-, libusb ? null
+, libusb-compat-0_1 ? null
 , gimpSupport ? false, gimp ? null
 }:
 
@@ -20,7 +20,7 @@ stdenv.mkDerivation rec {
 
   nativeBuildInputs = [ pkgconfig ];
   buildInputs = [libpng sane-backends sane-frontends libX11 gtk2 ]
-    ++ (if libusb != null then [libusb] else [])
+    ++ (if libusb-compat-0_1 != null then [libusb-compat-0_1] else [])
     ++ stdenv.lib.optional gimpSupport gimp;
 
   meta = {
diff --git a/pkgs/applications/misc/digitalbitbox/default.nix b/pkgs/applications/misc/digitalbitbox/default.nix
index a6ae45306552..95159d1927ab 100644
--- a/pkgs/applications/misc/digitalbitbox/default.nix
+++ b/pkgs/applications/misc/digitalbitbox/default.nix
@@ -7,7 +7,7 @@
 , libtool
 , qrencode
 , udev
-, libusb
+, libusb-compat-0_1
 , makeWrapper
 , pkgconfig
 , qtbase
@@ -70,7 +70,7 @@ in stdenv.mkDerivation rec {
     libevent
     libtool
     udev
-    libusb
+    libusb-compat-0_1
     qrencode
 
     qtbase
diff --git a/pkgs/applications/misc/garmin-plugin/default.nix b/pkgs/applications/misc/garmin-plugin/default.nix
index ba6868b62f6f..95cbdd9c19b5 100644
--- a/pkgs/applications/misc/garmin-plugin/default.nix
+++ b/pkgs/applications/misc/garmin-plugin/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, garmintools, libgcrypt, libusb, pkgconfig, tinyxml, zlib }:
+{ stdenv, fetchurl, garmintools, libgcrypt, libusb-compat-0_1, pkgconfig, tinyxml, zlib }:
 stdenv.mkDerivation {
   name = "garmin-plugin-0.3.26";
   src = fetchurl {
@@ -7,7 +7,7 @@ stdenv.mkDerivation {
   };
   sourceRoot = "GarminPlugin-0.3.26/src";
   nativeBuildInputs = [ pkgconfig ];
-  buildInputs = [ garmintools libusb libgcrypt tinyxml zlib ];
+  buildInputs = [ garmintools libusb-compat-0_1 libgcrypt tinyxml zlib ];
   configureFlags = [
     "--with-libgcrypt-prefix=${libgcrypt.dev}"
     "--with-garmintools-incdir=${garmintools}/include"
diff --git a/pkgs/applications/misc/golden-cheetah/default.nix b/pkgs/applications/misc/golden-cheetah/default.nix
index 3dffc5c77c2a..761d05e5f9f8 100644
--- a/pkgs/applications/misc/golden-cheetah/default.nix
+++ b/pkgs/applications/misc/golden-cheetah/default.nix
@@ -1,6 +1,6 @@
 { stdenv, fetchFromGitHub, mkDerivation
 , qtbase, qtsvg, qtserialport, qtwebengine, qtmultimedia, qttools
-, qtconnectivity, qtcharts, libusb
+, qtconnectivity, qtcharts, libusb-compat-0_1
 , yacc, flex, zlib, qmake, makeDesktopItem, makeWrapper
 }:
 
@@ -27,7 +27,7 @@ in mkDerivation rec {
 
   buildInputs = [
     qtbase qtsvg qtserialport qtwebengine qtmultimedia qttools zlib
-    qtconnectivity qtcharts libusb
+    qtconnectivity qtcharts libusb-compat-0_1
   ];
   nativeBuildInputs = [ flex makeWrapper qmake yacc ];
 
@@ -39,9 +39,9 @@ in mkDerivation rec {
     cp src/gcconfig.pri.in src/gcconfig.pri
     cp qwt/qwtconfig.pri.in qwt/qwtconfig.pri
     echo 'QMAKE_LRELEASE = ${qttools.dev}/bin/lrelease' >> src/gcconfig.pri
-    echo 'LIBUSB_INSTALL = ${libusb}' >> src/gcconfig.pri
-    echo 'LIBUSB_INCLUDE = ${libusb.dev}/include' >> src/gcconfig.pri
-    echo 'LIBUSB_LIBS = -L${libusb}/lib -lusb' >> src/gcconfig.pri
+    echo 'LIBUSB_INSTALL = ${libusb-compat-0_1}' >> src/gcconfig.pri
+    echo 'LIBUSB_INCLUDE = ${libusb-compat-0_1.dev}/include' >> src/gcconfig.pri
+    echo 'LIBUSB_LIBS = -L${libusb-compat-0_1}/lib -lusb' >> src/gcconfig.pri
     sed -i -e '21,23d' qwt/qwtconfig.pri # Removed forced installation to /usr/local
 
     # Use qtwebengine instead of qtwebkit
diff --git a/pkgs/applications/misc/lutris/chrootenv.nix b/pkgs/applications/misc/lutris/chrootenv.nix
index 84246f4ba124..4505432b236d 100644
--- a/pkgs/applications/misc/lutris/chrootenv.nix
+++ b/pkgs/applications/misc/lutris/chrootenv.nix
@@ -92,7 +92,7 @@ in buildFHSUserEnv {
   multiPkgs = pkgs: with pkgs; [
     # Common
     libsndfile libtheora libogg libvorbis libopus libGLU libpcap libpulseaudio
-    libao libevdev udev libgcrypt libxml2 libusb libpng libmpeg2 libv4l
+    libao libevdev udev libgcrypt libxml2 libusb-compat-0_1 libpng libmpeg2 libv4l
     libjpeg libxkbcommon libass libcdio libjack2 libsamplerate libzip libmad libaio
     libcap libtiff libva libgphoto2 libxslt libsndfile giflib zlib glib
     alsaLib zziplib bash dbus keyutils zip cabextract freetype unzip coreutils
diff --git a/pkgs/applications/misc/nut/default.nix b/pkgs/applications/misc/nut/default.nix
index ce80ae14f233..8f188818d4f7 100644
--- a/pkgs/applications/misc/nut/default.nix
+++ b/pkgs/applications/misc/nut/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, pkgconfig, neon, libusb, openssl, udev, avahi, freeipmi
+{ stdenv, fetchurl, pkgconfig, neon, libusb-compat-0_1, openssl, udev, avahi, freeipmi
 , libtool, makeWrapper, autoreconfHook, fetchpatch
 }:
 
@@ -19,7 +19,7 @@ stdenv.mkDerivation rec {
     })
   ];
 
-  buildInputs = [ neon libusb openssl udev avahi freeipmi ];
+  buildInputs = [ neon libusb-compat-0_1 openssl udev avahi freeipmi ];
 
   nativeBuildInputs = [ autoreconfHook libtool pkgconfig makeWrapper ];
 
@@ -38,7 +38,7 @@ stdenv.mkDerivation rec {
 
   postInstall = ''
     wrapProgram $out/bin/nut-scanner --prefix LD_LIBRARY_PATH : \
-      "$out/lib:${neon}/lib:${libusb.out}/lib:${avahi}/lib:${freeipmi}/lib"
+      "$out/lib:${neon}/lib:${libusb-compat-0_1.out}/lib:${avahi}/lib:${freeipmi}/lib"
   '';
 
   meta = with stdenv.lib; {
diff --git a/pkgs/applications/misc/qlandkartegt/garmindev.nix b/pkgs/applications/misc/qlandkartegt/garmindev.nix
index 213780842143..8705abd92596 100644
--- a/pkgs/applications/misc/qlandkartegt/garmindev.nix
+++ b/pkgs/applications/misc/qlandkartegt/garmindev.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, cmake, libusb }:
+{ stdenv, fetchurl, cmake, libusb-compat-0_1 }:
 
 stdenv.mkDerivation rec {
   pname = "garmindev";
@@ -11,7 +11,7 @@ stdenv.mkDerivation rec {
 
   nativeBuildInputs = [ cmake ];
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
   enableParallelBuilding = true;
 
diff --git a/pkgs/applications/misc/qlcplus/default.nix b/pkgs/applications/misc/qlcplus/default.nix
index c0b844d121af..77a24413bdd6 100644
--- a/pkgs/applications/misc/qlcplus/default.nix
+++ b/pkgs/applications/misc/qlcplus/default.nix
@@ -1,5 +1,5 @@
 { stdenv, mkDerivation, fetchFromGitHub, qmake, pkgconfig, udev
-, qtmultimedia, qtscript, alsaLib, ola, libftdi1, libusb
+, qtmultimedia, qtscript, alsaLib, ola, libftdi1, libusb-compat-0_1
 , libsndfile, libmad
 }:
 
@@ -16,7 +16,7 @@ mkDerivation rec {
 
   nativeBuildInputs = [ qmake pkgconfig ];
   buildInputs = [
-    udev qtmultimedia qtscript alsaLib ola libftdi1 libusb libsndfile libmad
+    udev qtmultimedia qtscript alsaLib ola libftdi1 libusb-compat-0_1 libsndfile libmad
   ];
 
   qmakeFlags = [ "INSTALLROOT=$(out)" ];
diff --git a/pkgs/applications/misc/subsurface/default.nix b/pkgs/applications/misc/subsurface/default.nix
index d262fb74c4b5..e189351022b9 100644
--- a/pkgs/applications/misc/subsurface/default.nix
+++ b/pkgs/applications/misc/subsurface/default.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchurl, fetchFromGitHub, autoreconfHook, cmake, wrapQtAppsHook, pkgconfig, qmake
-, curl, grantlee, libgit2, libusb, libssh2, libxml2, libxslt, libzip, zlib
+, curl, grantlee, libgit2, libusb-compat-0_1, libssh2, libxml2, libxslt, libzip, zlib
 , qtbase, qtconnectivity, qtlocation, qtsvg, qttools, qtwebkit, libXcomposite
 }:
 
@@ -83,7 +83,7 @@ in stdenv.mkDerivation {
 
   buildInputs = [
     libdc googlemaps
-    curl grantlee libgit2 libssh2 libusb libxml2 libxslt libzip
+    curl grantlee libgit2 libssh2 libusb-compat-0_1 libxml2 libxslt libzip
     qtbase qtconnectivity qtsvg qttools qtwebkit
   ];
 
diff --git a/pkgs/applications/radio/sdrangel/default.nix b/pkgs/applications/radio/sdrangel/default.nix
index 7cb64f92f3f4..6d0a19334dec 100644
--- a/pkgs/applications/radio/sdrangel/default.nix
+++ b/pkgs/applications/radio/sdrangel/default.nix
@@ -13,7 +13,7 @@ libav,
 libiio,
 libopus,
 libpulseaudio,
-libusb,
+libusb-compat-0_1,
 limesuite,
 mkDerivation,
 ocl-icd,
@@ -51,7 +51,7 @@ in mkDerivation rec {
 
   nativeBuildInputs = [ cmake pkgconfig ];
   buildInputs = [
-    glew opencv3 libusb boost libopus limesuite libav libiio libpulseaudio
+    glew opencv3 libusb-compat-0_1 boost libopus limesuite libav libiio libpulseaudio
     qtbase qtwebsockets qtmultimedia rtl-sdr airspy hackrf
     fftwFloat codec2' cm256cc serialdv
   ];
diff --git a/pkgs/applications/radio/soapysdr/default.nix b/pkgs/applications/radio/soapysdr/default.nix
index 36df6ad19d31..676f7d3c839e 100644
--- a/pkgs/applications/radio/soapysdr/default.nix
+++ b/pkgs/applications/radio/soapysdr/default.nix
@@ -1,6 +1,6 @@
 { stdenv, lib, lndir, makeWrapper
 , fetchFromGitHub, cmake
-, libusb, pkgconfig
+, libusb-compat-0_1, pkgconfig
 , usePython ? false
 , python, ncurses, swig2
 , extraPackages ? []
@@ -25,7 +25,7 @@ in stdenv.mkDerivation {
   };
 
   nativeBuildInputs = [ cmake makeWrapper pkgconfig ];
-  buildInputs = [ libusb ncurses ]
+  buildInputs = [ libusb-compat-0_1 ncurses ]
     ++ lib.optionals usePython [ python swig2 ];
 
   propagatedBuildInputs = lib.optional usePython python.pkgs.numpy;
diff --git a/pkgs/applications/radio/welle-io/default.nix b/pkgs/applications/radio/welle-io/default.nix
index 971399c4a229..05187440899b 100644
--- a/pkgs/applications/radio/welle-io/default.nix
+++ b/pkgs/applications/radio/welle-io/default.nix
@@ -1,6 +1,6 @@
 { mkDerivation, lib, fetchFromGitHub, cmake, pkgconfig
 , qtbase, qtcharts, qtmultimedia, qtquickcontrols, qtquickcontrols2
-, faad2, rtl-sdr, soapysdr-with-plugins, libusb, fftwSinglePrec, lame, mpg123 }:
+, faad2, rtl-sdr, soapysdr-with-plugins, libusb-compat-0_1, fftwSinglePrec, lame, mpg123 }:
 let
 
   version = "2.1";
@@ -23,7 +23,7 @@ in mkDerivation {
     faad2
     fftwSinglePrec
     lame
-    libusb
+    libusb-compat-0_1
     mpg123
     qtbase
     qtcharts
diff --git a/pkgs/applications/science/math/cemu/default.nix b/pkgs/applications/science/math/cemu/default.nix
index f91e5be51700..b41135229dd7 100644
--- a/pkgs/applications/science/math/cemu/default.nix
+++ b/pkgs/applications/science/math/cemu/default.nix
@@ -4,7 +4,7 @@
 , SDL2
 , libGL
 , libarchive
-, libusb
+, libusb-compat-0_1
 , qtbase
 , qmake
 , git
@@ -33,7 +33,7 @@ mkDerivation rec {
     SDL2
     libGL
     libarchive
-    libusb
+    libusb-compat-0_1
     qtbase
     libpng_apng
   ];
diff --git a/pkgs/applications/science/robotics/gazebo/default.nix b/pkgs/applications/science/robotics/gazebo/default.nix
index aea298b65485..86572e73c756 100644
--- a/pkgs/applications/science/robotics/gazebo/default.nix
+++ b/pkgs/applications/science/robotics/gazebo/default.nix
@@ -1,7 +1,7 @@
 { stdenv, fetchurl, cmake, pkgconfig, boost, protobuf, freeimage
   , boost-build, boost_process
   , xorg_sys_opengl, tbb, ogre, tinyxml-2
-  , libtar, glxinfo,  libusb, libxslt, ignition
+  , libtar, glxinfo,  libusb-compat-0_1, libxslt, ignition
   , pythonPackages, utillinux
 
   # these deps are hidden; cmake doesn't catch them
@@ -52,7 +52,7 @@ stdenv.mkDerivation rec {
     tinyxml-2
     libtar
     glxinfo
-    libusb
+    libusb-compat-0_1
     libxslt
     ignition.math2
     sdformat
diff --git a/pkgs/applications/video/kodi/default.nix b/pkgs/applications/video/kodi/default.nix
index c83705ac4160..e4da20c84879 100644
--- a/pkgs/applications/video/kodi/default.nix
+++ b/pkgs/applications/video/kodi/default.nix
@@ -25,7 +25,7 @@
 , rtmpSupport ? true, rtmpdump ? null
 , sambaSupport ? true, samba ? null
 , udevSupport ? true, udev ? null
-, usbSupport  ? false, libusb ? null
+, usbSupport  ? false, libusb-compat-0_1 ? null
 , vdpauSupport ? true, libvdpau ? null
 , useWayland ? false, wayland ? null, wayland-protocols ? null
 , waylandpp ?  null, libxkbcommon ? null
@@ -39,7 +39,7 @@ assert pulseSupport -> libpulseaudio != null;
 assert rtmpSupport  -> rtmpdump != null;
 assert sambaSupport -> samba != null;
 assert udevSupport  -> udev != null;
-assert usbSupport   -> libusb != null && ! udevSupport; # libusb won't be used if udev is avaliable
+assert usbSupport   -> libusb-compat-0_1 != null && ! udevSupport; # libusb-compat-0_1 won't be used if udev is avaliable
 assert vdpauSupport -> libvdpau != null;
 assert useWayland -> wayland != null && wayland-protocols != null && waylandpp != null && libxkbcommon != null;
 
@@ -189,7 +189,7 @@ in stdenv.mkDerivation {
     ++ lib.optional  rtmpSupport     rtmpdump
     ++ lib.optional  sambaSupport    samba
     ++ lib.optional  udevSupport     udev
-    ++ lib.optional  usbSupport      libusb
+    ++ lib.optional  usbSupport      libusb-compat-0_1
     ++ lib.optional  vdpauSupport    libvdpau
     ++ lib.optionals useWayland [
       wayland 
diff --git a/pkgs/development/arduino/arduino-core/default.nix b/pkgs/development/arduino/arduino-core/default.nix
index aa472512d148..3512dcbd2bcf 100644
--- a/pkgs/development/arduino/arduino-core/default.nix
+++ b/pkgs/development/arduino/arduino-core/default.nix
@@ -1,5 +1,5 @@
 { stdenv, lib, fetchFromGitHub, fetchurl, jdk, ant
-, libusb, libusb1, unzip, zlib, ncurses, readline
+, libusb-compat-0_1, libusb1, unzip, zlib, ncurses, readline
 , withGui ? false, gtk2 ? null, withTeensyduino ? false
   /* Packages needed for Teensyduino */
 , upx, fontconfig, xorg, gcc
@@ -42,7 +42,7 @@ let
     glib
     gtk2
     libpng12
-    libusb
+    libusb-compat-0_1
     pango
     udev
     xorg.libSM
@@ -96,7 +96,7 @@ stdenv.mkDerivation rec {
   };
 
 
-  buildInputs = [ jdk ant libusb libusb1 unzip zlib ncurses5 readline
+  buildInputs = [ jdk ant libusb-compat-0_1 libusb1 unzip zlib ncurses5 readline
   ] ++ stdenv.lib.optionals withTeensyduino [ upx ];
   downloadSrcList = builtins.attrValues externalDownloads;
   downloadDstList = builtins.attrNames externalDownloads;
@@ -129,7 +129,7 @@ stdenv.mkDerivation rec {
   javaPath = lib.makeBinPath [jdk];
 
   # Everything else will be patched into rpath
-  rpath = (lib.makeLibraryPath [zlib libusb libusb1 readline ncurses5 stdenv.cc.cc]);
+  rpath = (lib.makeLibraryPath [zlib libusb-compat-0_1 libusb1 readline ncurses5 stdenv.cc.cc]);
 
   installPhase = ''
     mkdir -p $out/share/arduino
diff --git a/pkgs/development/libraries/garmintools/default.nix b/pkgs/development/libraries/garmintools/default.nix
index a086648c9124..aa6ebfd33959 100644
--- a/pkgs/development/libraries/garmintools/default.nix
+++ b/pkgs/development/libraries/garmintools/default.nix
@@ -1,11 +1,11 @@
-{ stdenv, fetchurl, libusb }:
+{ stdenv, fetchurl, libusb-compat-0_1 }:
 stdenv.mkDerivation {
   name = "garmintools-0.10";
   src = fetchurl {
     url = "https://storage.googleapis.com/google-code-archive-downloads/v2/code.google.com/garmintools/garmintools-0.10.tar.gz";
     sha256 = "1vjc8h0z4kx2h52yc3chxn3wh1krn234fg12sggbia9zjrzhpmgz";
   };
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
   meta = {
     description = "Provides the ability to communicate with the Garmin Forerunner 305 via the USB interface";
     homepage = "https://code.google.com/archive/p/garmintools/"; # community clone at https://github.com/ianmartin/garmintools
diff --git a/pkgs/development/libraries/hamlib/default.nix b/pkgs/development/libraries/hamlib/default.nix
index 8a359314dee4..8ef8b55be522 100644
--- a/pkgs/development/libraries/hamlib/default.nix
+++ b/pkgs/development/libraries/hamlib/default.nix
@@ -1,4 +1,4 @@
-{stdenv, fetchurl, perl, python2, swig, gd, libxml2, tcl, libusb, pkgconfig,
+{stdenv, fetchurl, perl, python2, swig, gd, libxml2, tcl, libusb-compat-0_1, pkgconfig,
  boost, libtool, perlPackages }:
 
 stdenv.mkDerivation rec {
@@ -11,7 +11,7 @@ stdenv.mkDerivation rec {
   };
 
   buildInputs = [ perl perlPackages.ExtUtilsMakeMaker python2 swig gd libxml2
-                  tcl libusb pkgconfig boost libtool ];
+                  tcl libusb-compat-0_1 pkgconfig boost libtool ];
 
   configureFlags = [ "--with-perl-binding" "--with-python-binding"
                      "--with-tcl-binding" "--with-rigmatrix" ];
diff --git a/pkgs/development/libraries/libftdi/default.nix b/pkgs/development/libraries/libftdi/default.nix
index d483cc16f083..88c848397de3 100644
--- a/pkgs/development/libraries/libftdi/default.nix
+++ b/pkgs/development/libraries/libftdi/default.nix
@@ -1,4 +1,4 @@
-{stdenv, fetchurl, libusb}:
+{stdenv, fetchurl, libusb-compat-0_1}:
 
 with stdenv; mkDerivation rec {
   name = "libftdi-0.20";
@@ -8,9 +8,9 @@ with stdenv; mkDerivation rec {
     sha256 = "13l39f6k6gff30hsgh0wa2z422g9pyl91rh8a8zz6f34k2sxaxii";
   };
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
-  propagatedBuildInputs = [ libusb ];
+  propagatedBuildInputs = [ libusb-compat-0_1 ];
 
   # Hack to avoid TMPDIR in RPATHs.
   preFixup = ''rm -rf "$(pwd)" '';
diff --git a/pkgs/development/libraries/libnfc/default.nix b/pkgs/development/libraries/libnfc/default.nix
index c3661a233afd..ed7412d66110 100644
--- a/pkgs/development/libraries/libnfc/default.nix
+++ b/pkgs/development/libraries/libnfc/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, libusb, readline }:
+{ stdenv, fetchurl, libusb-compat-0_1, readline }:
 
 stdenv.mkDerivation {
   pname = "libnfc";
@@ -9,7 +9,7 @@ stdenv.mkDerivation {
     sha256 = "0wj0iwwcpmpalyk61aa7yc6i4p9hgdajkrgnlswgk0vnwbc78pll";
   };
 
-  buildInputs = [ libusb readline ];
+  buildInputs = [ libusb-compat-0_1 readline ];
 
   meta = with stdenv.lib; {
     description = "Open source library libnfc for Near Field Communication";
diff --git a/pkgs/development/libraries/libusb/default.nix b/pkgs/development/libraries/libusb-compat/0.1.nix
similarity index 100%
rename from pkgs/development/libraries/libusb/default.nix
rename to pkgs/development/libraries/libusb-compat/0.1.nix
diff --git a/pkgs/development/libraries/lirc/default.nix b/pkgs/development/libraries/lirc/default.nix
index 1aaba1599c0a..97079be09623 100644
--- a/pkgs/development/libraries/lirc/default.nix
+++ b/pkgs/development/libraries/lirc/default.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchurl, fetchpatch, autoreconfHook, pkgconfig, help2man, python3,
-  alsaLib, xlibsWrapper, libxslt, systemd, libusb, libftdi1 }:
+  alsaLib, xlibsWrapper, libxslt, systemd, libusb-compat-0_1, libftdi1 }:
 
 stdenv.mkDerivation rec {
   name = "lirc-0.10.1";
@@ -33,7 +33,7 @@ stdenv.mkDerivation rec {
   nativeBuildInputs = [ autoreconfHook pkgconfig help2man
     (python3.withPackages (p: with p; [ pyyaml setuptools ])) ];
 
-  buildInputs = [ alsaLib xlibsWrapper libxslt systemd libusb libftdi1 ];
+  buildInputs = [ alsaLib xlibsWrapper libxslt systemd libusb-compat-0_1 libftdi1 ];
 
   configureFlags = [
     "--sysconfdir=/etc"
diff --git a/pkgs/development/libraries/openct/default.nix b/pkgs/development/libraries/openct/default.nix
index f8977c1b59c2..27a832daf475 100644
--- a/pkgs/development/libraries/openct/default.nix
+++ b/pkgs/development/libraries/openct/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchFromGitHub, autoreconfHook, pkgconfig, pcsclite, libusb
+{ stdenv, fetchFromGitHub, autoreconfHook, pkgconfig, pcsclite, libusb-compat-0_1
 , doxygen, libxslt
 }:
 
@@ -26,7 +26,7 @@ stdenv.mkDerivation rec {
   ];
 
   nativeBuildInputs = [ autoreconfHook pkgconfig ];
-  buildInputs = [ pcsclite libusb doxygen libxslt ];
+  buildInputs = [ pcsclite libusb-compat-0_1 doxygen libxslt ];
 
   preInstall = ''
     mkdir -p $out/etc
diff --git a/pkgs/development/libraries/scmccid/default.nix b/pkgs/development/libraries/scmccid/default.nix
index 5b07482507c2..0d980d9d1a2b 100644
--- a/pkgs/development/libraries/scmccid/default.nix
+++ b/pkgs/development/libraries/scmccid/default.nix
@@ -1,4 +1,4 @@
-{stdenv, fetchurl, patchelf, libusb}:
+{stdenv, fetchurl, patchelf, libusb-compat-0_1}:
 
 assert stdenv ? cc && stdenv.cc.libc != null;
 
@@ -18,7 +18,7 @@ stdenv.mkDerivation {
   nativeBuildInputs = [ patchelf ];
 
   installPhase = ''
-    RPATH=${libusb.out}/lib:${stdenv.cc.libc.out}/lib
+    RPATH=${libusb-compat-0_1.out}/lib:${stdenv.cc.libc.out}/lib
 
     for a in proprietary/*/Contents/Linux/*.so*; do
         if ! test -L $a; then
diff --git a/pkgs/development/libraries/unicap/default.nix b/pkgs/development/libraries/unicap/default.nix
index 2c2b814b68df..87ca28fee983 100644
--- a/pkgs/development/libraries/unicap/default.nix
+++ b/pkgs/development/libraries/unicap/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, libusb, libraw1394, dcraw, intltool, perl, v4l-utils }:
+{ stdenv, fetchurl, libusb-compat-0_1, libraw1394, dcraw, intltool, perl, v4l-utils }:
 
 stdenv.mkDerivation rec {
   pname = "libunicap";
@@ -9,7 +9,7 @@ stdenv.mkDerivation rec {
     sha256 = "05zcnnm4dfc6idihfi0fq5xka6x86zi89wip2ca19yz768sd33s9";
   };
 
-  buildInputs = [ libusb libraw1394 dcraw intltool perl v4l-utils ];
+  buildInputs = [ libusb-compat-0_1 libraw1394 dcraw intltool perl v4l-utils ];
 
   patches = [
     # Debian has a patch that fixes the build.
diff --git a/pkgs/development/misc/msp430/mspdebug.nix b/pkgs/development/misc/msp430/mspdebug.nix
index 6bb6b683f55e..3c7ff00151a4 100644
--- a/pkgs/development/misc/msp430/mspdebug.nix
+++ b/pkgs/development/misc/msp430/mspdebug.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchFromGitHub, libusb, readline ? null }:
+{ stdenv, fetchFromGitHub, libusb-compat-0_1, readline ? null }:
 
 let
   version = "0.25";
@@ -12,7 +12,7 @@ in stdenv.mkDerivation {
     sha256 = "0prgwb5vx6fd4bj12ss1bbb6axj2kjyriyjxqrzd58s5jyyy8d3c";
   };
 
-  buildInputs = [ libusb readline ];
+  buildInputs = [ libusb-compat-0_1 readline ];
   makeFlags = [ "PREFIX=$(out)" "INSTALL=install" ] ++
     (if readline == null then [ "WITHOUT_READLINE=1" ] else []);
 
diff --git a/pkgs/development/mobile/webos/novacomd.nix b/pkgs/development/mobile/webos/novacomd.nix
index 4d62dd305d3a..932ec0e59d64 100644
--- a/pkgs/development/mobile/webos/novacomd.nix
+++ b/pkgs/development/mobile/webos/novacomd.nix
@@ -1,7 +1,7 @@
 { stdenv,
 fetchFromGitHub, fetchpatch,
 webos, cmake, pkgconfig,
-libusb }:
+libusb-compat-0_1 }:
 
 stdenv.mkDerivation rec {
   pname = "novacomd";
@@ -27,7 +27,7 @@ stdenv.mkDerivation rec {
 
   nativeBuildInputs = [ cmake pkgconfig webos.cmake-modules ];
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
   cmakeFlags = [ "-DWEBOS_TARGET_MACHINE_IMPL=host" ];
 
diff --git a/pkgs/development/mobile/xpwn/default.nix b/pkgs/development/mobile/xpwn/default.nix
index 9ec5977d5947..0c49a29b3222 100644
--- a/pkgs/development/mobile/xpwn/default.nix
+++ b/pkgs/development/mobile/xpwn/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchFromGitHub, cmake, zlib, libpng, bzip2, libusb, openssl }:
+{ stdenv, fetchFromGitHub, cmake, zlib, libpng, bzip2, libusb-compat-0_1, openssl }:
 
 stdenv.mkDerivation rec {
   pname = "xpwn";
@@ -22,7 +22,7 @@ stdenv.mkDerivation rec {
 
   strictDeps = true;
   nativeBuildInputs = [ cmake ];
-  buildInputs = [ zlib libpng bzip2 libusb openssl ];
+  buildInputs = [ zlib libpng bzip2 libusb-compat-0_1 openssl ];
 
   meta = with stdenv.lib; {
     homepage    = "http://planetbeing.lighthouseapp.com/projects/15246-xpwn";
diff --git a/pkgs/development/tools/analysis/radare2/default.nix b/pkgs/development/tools/analysis/radare2/default.nix
index 37dc9e51beab..48a1f20cfd96 100644
--- a/pkgs/development/tools/analysis/radare2/default.nix
+++ b/pkgs/development/tools/analysis/radare2/default.nix
@@ -1,7 +1,7 @@
 {stdenv, fetchFromGitHub
 , buildPackages
 , pkgconfig
-, libusb, readline, libewf, perl, zlib, openssl
+, libusb-compat-0_1, readline, libewf, perl, zlib, openssl
 , libuv, file, libzip, xxHash
 , gtk2 ? null, vte ? null, gtkdialog ? null
 , python3 ? null
@@ -84,7 +84,7 @@ let
       depsBuildBuild = [ buildPackages.stdenv.cc ];
 
       nativeBuildInputs = [ pkgconfig ];
-      buildInputs = [ file readline libusb libewf perl zlib openssl libuv ]
+      buildInputs = [ file readline libusb-compat-0_1 libewf perl zlib openssl libuv ]
         ++ optional useX11 [ gtkdialog vte gtk2 ]
         ++ optional rubyBindings [ ruby ]
         ++ optional pythonBindings [ python3 ]
diff --git a/pkgs/development/tools/misc/avrdude/default.nix b/pkgs/development/tools/misc/avrdude/default.nix
index bca091d63095..bb0520cf28ef 100644
--- a/pkgs/development/tools/misc/avrdude/default.nix
+++ b/pkgs/development/tools/misc/avrdude/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, yacc, flex, libusb, libelf, libftdi1, readline
+{ stdenv, fetchurl, yacc, flex, libusb-compat-0_1, libelf, libftdi1, readline
 # docSupport is a big dependency, disabled by default
 , docSupport ? false, texLive ? null, texinfo ? null, texi2html ? null
 }:
@@ -15,7 +15,7 @@ stdenv.mkDerivation rec {
 
   configureFlags = stdenv.lib.optionals docSupport "--enable-doc";
 
-  buildInputs = [ yacc flex libusb libelf libftdi1 readline ]
+  buildInputs = [ yacc flex libusb-compat-0_1 libelf libftdi1 readline ]
     ++ stdenv.lib.optionals docSupport [ texLive texinfo texi2html ];
 
   meta = with stdenv.lib; {
diff --git a/pkgs/development/tools/misc/blackmagic/default.nix b/pkgs/development/tools/misc/blackmagic/default.nix
index 224cf16d7632..6e733cfe28ab 100644
--- a/pkgs/development/tools/misc/blackmagic/default.nix
+++ b/pkgs/development/tools/misc/blackmagic/default.nix
@@ -1,5 +1,5 @@
 { stdenv, lib, fetchFromGitHub
-, gcc-arm-embedded, libftdi1, libusb, pkgconfig
+, gcc-arm-embedded, libftdi1, libusb-compat-0_1, pkgconfig
 , python, pythonPackages
 }:
 
@@ -25,7 +25,7 @@ stdenv.mkDerivation rec {
 
   buildInputs = [
     libftdi1
-    libusb
+    libusb-compat-0_1
     python
     pythonPackages.intelhex
   ];
diff --git a/pkgs/development/tools/misc/dfu-programmer/default.nix b/pkgs/development/tools/misc/dfu-programmer/default.nix
index 10e6dc0d8b82..a474ccc7e594 100644
--- a/pkgs/development/tools/misc/dfu-programmer/default.nix
+++ b/pkgs/development/tools/misc/dfu-programmer/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, libusb }:
+{ stdenv, fetchurl, libusb-compat-0_1 }:
 let
   version = "0.7.2";
 in
@@ -6,7 +6,7 @@ stdenv.mkDerivation rec {
   pname = "dfu-programmer";
   inherit version;
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
   src = fetchurl {
     url = "mirror://sourceforge/dfu-programmer/${pname}-${version}.tar.gz";
diff --git a/pkgs/development/tools/misc/micronucleus/default.nix b/pkgs/development/tools/misc/micronucleus/default.nix
index 9fbafebb10c5..890439adc6e9 100644
--- a/pkgs/development/tools/misc/micronucleus/default.nix
+++ b/pkgs/development/tools/misc/micronucleus/default.nix
@@ -1,7 +1,7 @@
 {
   pkgs
 , stdenv
-, libusb
+, libusb-compat-0_1
 , fetchFromGitHub
 , lib
 }:
@@ -18,7 +18,7 @@ stdenv.mkDerivation rec {
      sha256 = "14msy9amlbflw5mqrbs57b7bby3nsgx43srr7215zyhfdgsla0in";
    };
 
-   buildInputs = [ libusb ];
+   buildInputs = [ libusb-compat-0_1 ];
    makeFlags = stdenv.lib.optionals stdenv.isDarwin [ "CC=cc" ];
 
    installPhase = ''
diff --git a/pkgs/development/tools/misc/teensy-loader-cli/default.nix b/pkgs/development/tools/misc/teensy-loader-cli/default.nix
index e03320f84295..62c480707cdd 100644
--- a/pkgs/development/tools/misc/teensy-loader-cli/default.nix
+++ b/pkgs/development/tools/misc/teensy-loader-cli/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchFromGitHub, go-md2man, installShellFiles, libusb }:
+{ stdenv, fetchFromGitHub, go-md2man, installShellFiles, libusb-compat-0_1 }:
 
 stdenv.mkDerivation rec {
   pname = "teensy-loader-cli";
@@ -11,7 +11,7 @@ stdenv.mkDerivation rec {
     sha256 = "1yx8vsh6b29pqr4zb6sx47429i9x51hj9psn8zksfz75j5ivfd5i";
   };
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
   nativeBuildInputs = [ go-md2man installShellFiles ];
 
diff --git a/pkgs/development/tools/misc/wishbone-tool/default.nix b/pkgs/development/tools/misc/wishbone-tool/default.nix
index 8c2e27d64507..d900d14e33c2 100644
--- a/pkgs/development/tools/misc/wishbone-tool/default.nix
+++ b/pkgs/development/tools/misc/wishbone-tool/default.nix
@@ -1,4 +1,4 @@
-{ lib, fetchFromGitHub, rustPlatform, libusb }:
+{ lib, fetchFromGitHub, rustPlatform, libusb-compat-0_1 }:
 
 let
   version = "0.6.9";
@@ -21,7 +21,7 @@ rustPlatform.buildRustPackage {
   '';
   cargoSha256 = "0d5kcwy0cgxqfxf2xysw65ng84q4knhp4fgvh6dwqhf0nsca9gvs";
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
   meta = with lib; {
     description = "Manipulate a Wishbone device over some sort of bridge";
diff --git a/pkgs/development/tools/misc/xc3sprog/default.nix b/pkgs/development/tools/misc/xc3sprog/default.nix
index b39e9028afda..1ccd6c2ec4f2 100644
--- a/pkgs/development/tools/misc/xc3sprog/default.nix
+++ b/pkgs/development/tools/misc/xc3sprog/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchsvn, cmake, libusb, libftdi }:
+{ stdenv, fetchsvn, cmake, libusb-compat-0_1, libftdi }:
 
 # The xc3sprog project doesn't seem to make proper releases, they only put out
 # prebuilt binary subversion snapshots on sourceforge.
@@ -13,7 +13,7 @@ stdenv.mkDerivation rec {
     rev = version;
   };
 
-  buildInputs = [ cmake libusb libftdi ];
+  buildInputs = [ cmake libusb-compat-0_1 libftdi ];
 
   meta = with stdenv.lib; {
     description = "Command-line tools for programming FPGAs, microcontrollers and PROMs via JTAG";
diff --git a/pkgs/misc/cups/drivers/samsung/1.00.36/default.nix b/pkgs/misc/cups/drivers/samsung/1.00.36/default.nix
index 308be5337d09..4088ce700de2 100644
--- a/pkgs/misc/cups/drivers/samsung/1.00.36/default.nix
+++ b/pkgs/misc/cups/drivers/samsung/1.00.36/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, cups, libusb, libxml2, perl }:
+{ stdenv, fetchurl, cups, libusb-compat-0_1, libxml2, perl }:
 
 let
 
@@ -17,7 +17,7 @@ in stdenv.mkDerivation rec {
 
   buildInputs = [
     cups
-    libusb
+    libusb-compat-0_1
     libxml2
     perl
   ];
@@ -91,7 +91,7 @@ in stdenv.mkDerivation rec {
     done
 
     patchelf --set-rpath "$out/lib:${stdenv.lib.getLib cups}/lib" "$out/lib/libscmssc.so"
-    patchelf --set-rpath "$out/lib:${libxml2.out}/lib:${libusb.out}/lib" "$out/lib/sane/libsane-smfp.so.1.0.1"
+    patchelf --set-rpath "$out/lib:${libxml2.out}/lib:${libusb-compat-0_1.out}/lib" "$out/lib/sane/libsane-smfp.so.1.0.1"
 
     ln -s ${stdenv.cc.cc.lib}/lib/libstdc++.so.6 $out/lib/
   '';
diff --git a/pkgs/misc/cups/drivers/samsung/1.00.37.nix b/pkgs/misc/cups/drivers/samsung/1.00.37.nix
index b7e75c2a16a9..c205560706f6 100644
--- a/pkgs/misc/cups/drivers/samsung/1.00.37.nix
+++ b/pkgs/misc/cups/drivers/samsung/1.00.37.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, cups, libusb, libxml2 }:
+{ stdenv, fetchurl, cups, libusb-compat-0_1, libxml2 }:
 
 let
 
@@ -17,7 +17,7 @@ in stdenv.mkDerivation rec {
 
   buildInputs = [
     cups
-    libusb
+    libusb-compat-0_1
     libxml2
   ];
 
@@ -74,7 +74,7 @@ in stdenv.mkDerivation rec {
     done
 
     patchelf --set-rpath "$out/lib:${stdenv.lib.getLib cups}/lib" "$out/lib/libscmssc.so"
-    patchelf --set-rpath "$out/lib:${libxml2.out}/lib:${libusb.out}/lib" "$out/lib/sane/libsane-smfp.so.1.0.1"
+    patchelf --set-rpath "$out/lib:${libxml2.out}/lib:${libusb-compat-0_1.out}/lib" "$out/lib/sane/libsane-smfp.so.1.0.1"
 
     ln -s ${stdenv.cc.cc.lib}/lib/libstdc++.so.6 $out/lib/
   '';
diff --git a/pkgs/misc/cups/drivers/samsung/4.01.17.nix b/pkgs/misc/cups/drivers/samsung/4.01.17.nix
index 755003e4d300..5de93b20cb80 100644
--- a/pkgs/misc/cups/drivers/samsung/4.01.17.nix
+++ b/pkgs/misc/cups/drivers/samsung/4.01.17.nix
@@ -11,14 +11,14 @@
 # }
 # (This advice was tested on the 1st November 2016.)
 
-{ stdenv, fetchurl, cups, libusb }:
+{ stdenv, fetchurl, cups, libusb-compat-0_1 }:
 
 # Do not bump lightly! Visit <http://www.bchemnet.com/suldr/supported.html>
 # to see what will break when upgrading. Consider a new versioned attribute.
 let
   installationPath = if stdenv.hostPlatform.system == "x86_64-linux" then "x86_64" else "i386";
   appendPath = if stdenv.hostPlatform.system == "x86_64-linux" then "64" else "";
-  libPath = stdenv.lib.makeLibraryPath [ cups libusb ] + ":$out/lib:${stdenv.cc.cc.lib}/lib${appendPath}";
+  libPath = stdenv.lib.makeLibraryPath [ cups libusb-compat-0_1 ] + ":$out/lib:${stdenv.cc.cc.lib}/lib${appendPath}";
 in stdenv.mkDerivation rec {
   pname = "samsung-UnifiedLinuxDriver";
   version = "4.01.17";
diff --git a/pkgs/misc/drivers/epkowa/default.nix b/pkgs/misc/drivers/epkowa/default.nix
index ecf79a953fe3..9724e68a04df 100644
--- a/pkgs/misc/drivers/epkowa/default.nix
+++ b/pkgs/misc/drivers/epkowa/default.nix
@@ -3,7 +3,7 @@ pkgconfig, libtool,
 gtk2,
 libxml2,
 libxslt,
-libusb,
+libusb-compat-0_1,
 sane-backends,
 rpm, cpio,
 getopt,
@@ -263,7 +263,7 @@ stdenv.mkDerivation rec {
     gtk2
     libxml2
     libtool
-    libusb
+    libusb-compat-0_1
     sane-backends
     makeWrapper
   ];
diff --git a/pkgs/misc/drivers/gutenprint/default.nix b/pkgs/misc/drivers/gutenprint/default.nix
index 96c0968882d3..9946f499329c 100644
--- a/pkgs/misc/drivers/gutenprint/default.nix
+++ b/pkgs/misc/drivers/gutenprint/default.nix
@@ -2,7 +2,7 @@
 { stdenv, lib, fetchurl, makeWrapper, pkgconfig
 , ijs, zlib
 , gimp2Support ? false, gimp
-, cupsSupport ? true, cups, libusb, perl
+, cupsSupport ? true, cups, libusb-compat-0_1, perl
 }:
 
 stdenv.mkDerivation rec {
@@ -17,7 +17,7 @@ stdenv.mkDerivation rec {
   buildInputs =
     [ ijs zlib ]
     ++ lib.optionals gimp2Support [ gimp.gtk gimp ]
-    ++ lib.optionals cupsSupport [ cups libusb perl ];
+    ++ lib.optionals cupsSupport [ cups libusb-compat-0_1 perl ];
 
   configureFlags = lib.optionals cupsSupport [
     "--disable-static-genppd" # should be harmless on NixOS
diff --git a/pkgs/os-specific/linux/g15daemon/default.nix b/pkgs/os-specific/linux/g15daemon/default.nix
index d00bf2f74335..c670fc86d13b 100644
--- a/pkgs/os-specific/linux/g15daemon/default.nix
+++ b/pkgs/os-specific/linux/g15daemon/default.nix
@@ -5,7 +5,7 @@
 , fetchpatch
 , patchelf
 , freetype
-, libusb
+, libusb-compat-0_1
 }:
 let
   license = lib.licenses.gpl2;
@@ -25,7 +25,7 @@ let
       sha256 = "1mkrf622n0cmz57lj8w9q82a9dcr1lmyyxbnrghrxzb6gvifnbqk";
     };
 
-    buildInputs = [ libusb ];
+    buildInputs = [ libusb-compat-0_1 ];
 
     enableParallelBuilding = true;
 
diff --git a/pkgs/servers/monitoring/lcdproc/default.nix b/pkgs/servers/monitoring/lcdproc/default.nix
index 927c7945b916..e469ee6b4082 100644
--- a/pkgs/servers/monitoring/lcdproc/default.nix
+++ b/pkgs/servers/monitoring/lcdproc/default.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchFromGitHub, autoreconfHook, makeWrapper, pkgconfig
-, doxygen, freetype, libX11, libftdi, libusb, libusb1, ncurses, perl }:
+, doxygen, freetype, libX11, libftdi, libusb-compat-0_1, libusb1, ncurses, perl }:
 
 stdenv.mkDerivation rec {
   pname = "lcdproc";
@@ -22,7 +22,7 @@ stdenv.mkDerivation rec {
     "--with-pidfile-dir=/run"
   ];
 
-  buildInputs = [ freetype libX11 libftdi libusb libusb1 ncurses ];
+  buildInputs = [ freetype libX11 libftdi libusb-compat-0_1 libusb1 ncurses ];
   nativeBuildInputs = [ autoreconfHook doxygen makeWrapper pkgconfig ];
 
   # In 0.5.9: gcc: error: libbignum.a: No such file or directory
diff --git a/pkgs/tools/bluetooth/obex-data-server/default.nix b/pkgs/tools/bluetooth/obex-data-server/default.nix
index 15661d6e360d..f95869e789cb 100644
--- a/pkgs/tools/bluetooth/obex-data-server/default.nix
+++ b/pkgs/tools/bluetooth/obex-data-server/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, pkgconfig, libusb, glib, dbus-glib, bluez, openobex, dbus }:
+{ stdenv, fetchurl, pkgconfig, libusb-compat-0_1, glib, dbus-glib, bluez, openobex, dbus }:
 
 stdenv.mkDerivation rec {
   name = "obex-data-server-0.4.6";
@@ -9,7 +9,7 @@ stdenv.mkDerivation rec {
   };
 
   nativeBuildInputs = [ pkgconfig ];
-  buildInputs = [ libusb glib dbus-glib bluez openobex dbus ];
+  buildInputs = [ libusb-compat-0_1 glib dbus-glib bluez openobex dbus ];
 
   patches = [ ./obex-data-server-0.4.6-build-fixes-1.patch ];
 
diff --git a/pkgs/tools/bluetooth/openobex/default.nix b/pkgs/tools/bluetooth/openobex/default.nix
index ccf2eee1bb13..7ac0234852c1 100644
--- a/pkgs/tools/bluetooth/openobex/default.nix
+++ b/pkgs/tools/bluetooth/openobex/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, pkgconfig, bluez, libusb, cmake }:
+{ stdenv, fetchurl, pkgconfig, bluez, libusb-compat-0_1, cmake }:
    
 stdenv.mkDerivation rec {
   name = "openobex-1.7.2";
@@ -9,7 +9,7 @@ stdenv.mkDerivation rec {
   };
 
   nativeBuildInputs = [ pkgconfig cmake ];
-  buildInputs = [ bluez libusb ];
+  buildInputs = [ bluez libusb-compat-0_1 ];
 
   configureFlags = [ "--enable-apps" ];
 
diff --git a/pkgs/tools/misc/gnokii/default.nix b/pkgs/tools/misc/gnokii/default.nix
index c0e516a15ad3..25c316661917 100644
--- a/pkgs/tools/misc/gnokii/default.nix
+++ b/pkgs/tools/misc/gnokii/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, intltool, perl, gettext, libusb, pkgconfig, bluez
+{ stdenv, fetchurl, intltool, perl, gettext, libusb-compat-0_1, pkgconfig, bluez
 , readline, pcsclite, libical, gtk2, glib, libXpm }:
 
 stdenv.mkDerivation rec {
@@ -11,7 +11,7 @@ stdenv.mkDerivation rec {
   };
 
   buildInputs = [
-    perl intltool gettext libusb
+    perl intltool gettext libusb-compat-0_1
     glib gtk2 pkgconfig bluez readline
     libXpm pcsclite libical
   ];
diff --git a/pkgs/tools/misc/grub/2.0x.nix b/pkgs/tools/misc/grub/2.0x.nix
index a64df8669812..4e00a4ddd49c 100644
--- a/pkgs/tools/misc/grub/2.0x.nix
+++ b/pkgs/tools/misc/grub/2.0x.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchgit, flex, bison, python, autoconf, automake, gnulib, libtool
-, gettext, ncurses, libusb, freetype, qemu, lvm2, unifont, pkgconfig
+, gettext, ncurses, libusb-compat-0_1, freetype, qemu, lvm2, unifont, pkgconfig
 , fuse # only needed for grub-mount
 , zfs ? null
 , efiSupport ? false
@@ -54,7 +54,7 @@ stdenv.mkDerivation rec {
   ];
 
   nativeBuildInputs = [ bison flex python pkgconfig autoconf automake ];
-  buildInputs = [ ncurses libusb freetype gettext lvm2 fuse libtool ]
+  buildInputs = [ ncurses libusb-compat-0_1 freetype gettext lvm2 fuse libtool ]
     ++ optional doCheck qemu
     ++ optional zfsSupport zfs;
 
diff --git a/pkgs/tools/misc/grub/trusted.nix b/pkgs/tools/misc/grub/trusted.nix
index 27676c4745b6..f14758a3ae75 100644
--- a/pkgs/tools/misc/grub/trusted.nix
+++ b/pkgs/tools/misc/grub/trusted.nix
@@ -1,5 +1,5 @@
 { stdenv, fetchurl, fetchgit, autogen, flex, bison, python, autoconf, automake
-, gettext, ncurses, libusb, freetype, qemu, lvm2
+, gettext, ncurses, libusb-compat-0_1, freetype, qemu, lvm2
 , for_HP_laptop ? false
 }:
 
@@ -45,7 +45,7 @@ stdenv.mkDerivation rec {
         };
 
   nativeBuildInputs = [ autogen flex bison python autoconf automake ];
-  buildInputs = [ ncurses libusb freetype gettext lvm2 ]
+  buildInputs = [ ncurses libusb-compat-0_1 freetype gettext lvm2 ]
     ++ optional doCheck qemu;
 
   hardeningDisable = [ "stackprotector" "pic" ];
diff --git a/pkgs/tools/misc/pk2cmd/default.nix b/pkgs/tools/misc/pk2cmd/default.nix
index 97628da67f76..8c7e5b8bcf22 100644
--- a/pkgs/tools/misc/pk2cmd/default.nix
+++ b/pkgs/tools/misc/pk2cmd/default.nix
@@ -1,4 +1,4 @@
-{stdenv, fetchurl, libusb, makeWrapper}:
+{stdenv, fetchurl, libusb-compat-0_1, makeWrapper}:
 
 stdenv.mkDerivation {
   name = "pk2cmd-1.20";
@@ -7,7 +7,7 @@ stdenv.mkDerivation {
     sha256 = "1yjpi2qshnqfpan4w3ggakkr3znfrx5cxkny92ka7v9na3g2fc4h";
   };
 
-  makeFlags = [ "LIBUSB=${libusb.dev}" "linux" ];
+  makeFlags = [ "LIBUSB=${libusb-compat-0_1.dev}" "linux" ];
 
   installPhase = ''
     mkdir -p $out/bin $out/share/pk2
@@ -16,7 +16,7 @@ stdenv.mkDerivation {
     wrapProgram $out/bin/pk2cmd --prefix PATH : $out/share/pk2
   '';
 
-  buildInputs = [ libusb makeWrapper ];
+  buildInputs = [ libusb-compat-0_1 makeWrapper ];
 
   meta = {
     homepage = "https://www.microchip.com/pickit2";
diff --git a/pkgs/tools/misc/sixpair/default.nix b/pkgs/tools/misc/sixpair/default.nix
index fafee99db5af..f738ed71ec7a 100644
--- a/pkgs/tools/misc/sixpair/default.nix
+++ b/pkgs/tools/misc/sixpair/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, libusb }:
+{ stdenv, fetchurl, libusb-compat-0_1 }:
 stdenv.mkDerivation {
   name = "sixpair-2007-04-18";
 
@@ -10,7 +10,7 @@ stdenv.mkDerivation {
   # hcitool is depricated
   patches = [ ./hcitool.patch ];
 
-  buildInputs = [ libusb ];
+  buildInputs = [ libusb-compat-0_1 ];
 
   unpackPhase = ''
     cp $src sixpair.c
diff --git a/pkgs/tools/misc/urjtag/default.nix b/pkgs/tools/misc/urjtag/default.nix
index 67b25eaca82f..2056fb9d0a5a 100644
--- a/pkgs/tools/misc/urjtag/default.nix
+++ b/pkgs/tools/misc/urjtag/default.nix
@@ -1,5 +1,5 @@
 { stdenv, autoconf, automake, pkgconfig, gettext, libtool, bison
-, flex, which, subversion, fetchsvn, makeWrapper, libftdi, libusb, readline
+, flex, which, subversion, fetchsvn, makeWrapper, libftdi, libusb-compat-0_1, readline
 , python3
 , svfSupport ? true
 , bsdlSupport ? true
@@ -19,7 +19,7 @@ stdenv.mkDerivation {
 
   nativeBuildInputs = [ pkgconfig ];
   buildInputs = [ gettext autoconf automake libtool bison flex which
-    subversion makeWrapper readline libftdi libusb python3 ];
+    subversion makeWrapper readline libftdi libusb-compat-0_1 python3 ];
 
   configureFlags = [
     (stdenv.lib.enableFeature svfSupport   "svf")
diff --git a/pkgs/tools/misc/xburst-tools/default.nix b/pkgs/tools/misc/xburst-tools/default.nix
index 48045999329a..12acbcfbe1c8 100644
--- a/pkgs/tools/misc/xburst-tools/default.nix
+++ b/pkgs/tools/misc/xburst-tools/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchgit, libusb, libusb1, autoconf, automake, libconfuse, pkgconfig
+{ stdenv, fetchgit, libusb-compat-0_1, libusb1, autoconf, automake, libconfuse, pkgconfig
 , gccCross ? null
 }:
 
@@ -30,7 +30,7 @@ stdenv.mkDerivation {
   dontCrossStrip = true;
 
   nativeBuildInputs = [ autoconf automake pkgconfig ];
-  buildInputs = [ libusb libusb1 libconfuse ] ++
+  buildInputs = [ libusb-compat-0_1 libusb1 libconfuse ] ++
     stdenv.lib.optional (gccCross != null) gccCross;
 
   meta = {
diff --git a/pkgs/tools/security/gnupg/20.nix b/pkgs/tools/security/gnupg/20.nix
index ea9001607526..f5b693fed35a 100644
--- a/pkgs/tools/security/gnupg/20.nix
+++ b/pkgs/tools/security/gnupg/20.nix
@@ -4,7 +4,7 @@
 # Each of the dependencies below are optional.
 # Gnupg can be built without them at the cost of reduced functionality.
 , pinentry ? null, guiSupport ? false
-, openldap ? null, bzip2 ? null, libusb ? null, curl ? null
+, openldap ? null, bzip2 ? null, libusb-compat-0_1 ? null, curl ? null
 }:
 
 with stdenv.lib;
@@ -22,7 +22,7 @@ stdenv.mkDerivation rec {
 
   buildInputs
     = [ readline zlib libgpgerror libgcrypt libassuan libksba pth
-        openldap bzip2 libusb curl libiconv ];
+        openldap bzip2 libusb-compat-0_1 curl libiconv ];
 
   patches = [ ./gpgkey2ssh-20.patch ];
 
diff --git a/pkgs/tools/security/libacr38u/default.nix b/pkgs/tools/security/libacr38u/default.nix
index 45d0279099fd..b56c15af3d62 100644
--- a/pkgs/tools/security/libacr38u/default.nix
+++ b/pkgs/tools/security/libacr38u/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, pkgconfig, pcsclite , libusb }:
+{ stdenv, fetchurl, pkgconfig, pcsclite , libusb-compat-0_1 }:
 
 stdenv.mkDerivation {
   version = "1.7.11";
@@ -12,7 +12,7 @@ stdenv.mkDerivation {
   doCheck = true;
 
   nativeBuildInputs = [ pkgconfig ];
-  buildInputs = [ pcsclite libusb ];
+  buildInputs = [ pcsclite libusb-compat-0_1 ];
 
   preBuild = ''
     makeFlagsArray=(usbdropdir="$out/pcsc/drivers");
diff --git a/pkgs/tools/security/pcsc-scm-scl011/default.nix b/pkgs/tools/security/pcsc-scm-scl011/default.nix
index b400d628fd77..62f4c3e85564 100644
--- a/pkgs/tools/security/pcsc-scm-scl011/default.nix
+++ b/pkgs/tools/security/pcsc-scm-scl011/default.nix
@@ -1,4 +1,4 @@
-{ stdenv, fetchurl, unzip, libusb }:
+{ stdenv, fetchurl, unzip, libusb-compat-0_1 }:
 
 let
   arch = if stdenv.hostPlatform.system == "i686-linux" then "32"
@@ -30,7 +30,7 @@ stdenv.mkDerivation rec {
     cp -r proprietary/*.bundle $out/pcsc/drivers
   '';
 
-  libPath = stdenv.lib.makeLibraryPath [ libusb ];
+  libPath = stdenv.lib.makeLibraryPath [ libusb-compat-0_1 ];
 
   fixupPhase = ''
     patchelf --set-rpath $libPath \
diff --git a/pkgs/top-level/aliases.nix b/pkgs/top-level/aliases.nix
index 5b26ecb2da6e..910a8f3c67c4 100644
--- a/pkgs/top-level/aliases.nix
+++ b/pkgs/top-level/aliases.nix
@@ -249,6 +249,7 @@ mapAliases ({
   libtxc_dxtn = throw "removed 2020-03-16, now integrated in Mesa";
   libtxc_dxtn_s2tc = throw "removed 2020-03-16, now integrated in Mesa";
   libudev = udev; # added 2018-04-25
+  libusb = libusb-compat-0_1; # added 2020-04-28
   libsexy = throw "libsexy has been removed from nixpkgs, as it's abandoned and no package needed it."; # 2019-12-10
   libqmatrixclient = throw "libqmatrixclient was renamed to libquotient"; # added 2020-04-09
   links = links2; # added 2016-01-31
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index 0628fdaad86b..ad6b2b1a53a6 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -13356,7 +13356,7 @@ in
 
   liburcu = callPackage ../development/libraries/liburcu { };
 
-  libusb = callPackage ../development/libraries/libusb {};
+  libusb-compat-0_1 = callPackage ../development/libraries/libusb-compat/0.1.nix {};
 
   libusb1 = callPackage ../development/libraries/libusb1 {
     inherit (darwin) libobjc;