diff --git a/pkgs/development/libraries/libmilter/darwin.patch b/pkgs/development/libraries/libmilter/darwin.patch
new file mode 100644
index 000000000000..be46662d6b38
--- /dev/null
+++ b/pkgs/development/libraries/libmilter/darwin.patch
@@ -0,0 +1,28 @@
+Fix build issues on Darwin.
+
+--- a/devtools/OS/Darwin	2014-03-05 01:59:45.000000000 +0100
++++ b/devtools/OS/Darwin	2020-05-18 14:47:57.000000000 +0200
+@@ -8,6 +8,8 @@
+ #    We look a lot more like 4.4BSD than NeXTStep or OpenStep.
+ #
+ define(`confCC', `cc -traditional-cpp -pipe ${Extra_CC_Flags}')
++define(`confCCOPTS_SO', `-fPIC')
++define(`confSOEXT', `dylib')
+ define(`confMAPDEF', `-DNEWDB -DNIS -DMAP_REGEX -DNETINFO -DAUTO_NETINFO_ALIASES -DAUTO_NETINFO_HOSTS')
+ define(`confENVDEF', `-DDARWIN')
+ define(`confLDOPTS', `${Extra_LD_Flags}')
+--- a/sendmail/sendmail.h	2020-05-18 14:51:17.000000000 +0200
++++ b/sendmail/sendmail.h	2020-05-18 14:51:00.000000000 +0200
+@@ -104,7 +104,11 @@
+ # endif /* NETX25 */
+ 
+ # if NAMED_BIND
+-#  include <arpa/nameser.h>
++#  ifdef __APPLE__
++#   include <arpa/nameser_compat.h>
++#  else
++#   include <arpa/nameser.h>
++#  endif
+ #  ifdef NOERROR
+ #   undef NOERROR		/* avoid <sys/streams.h> conflict */
+ #  endif /* NOERROR */
diff --git a/pkgs/development/libraries/libmilter/default.nix b/pkgs/development/libraries/libmilter/default.nix
index 60ced27beac7..f937d818a559 100644
--- a/pkgs/development/libraries/libmilter/default.nix
+++ b/pkgs/development/libraries/libmilter/default.nix
@@ -32,7 +32,7 @@ stdenv.mkDerivation rec {
     sh Build -f ./a.m4
   '';
 
-  patches = [ ./install.patch ./sharedlib.patch ./glibc-2.30.patch ];
+  patches = [ ./install.patch ./sharedlib.patch ./glibc-2.30.patch ./darwin.patch ];
 
   nativeBuildInputs = [ m4 ];