diff --git a/pkgs/development/interpreters/clisp/2.44.1.nix b/pkgs/development/interpreters/clisp/2.44.1.nix
index 66f53831374f..682978a5ac8d 100644
--- a/pkgs/development/interpreters/clisp/2.44.1.nix
+++ b/pkgs/development/interpreters/clisp/2.44.1.nix
@@ -43,7 +43,7 @@ stdenv.mkDerivation rec {
     cd builddir
   '';
 
-  NIX_CFLAGS_COMPILE="-O0";
+  NIX_CFLAGS_COMPILE = "-O0 ${stdenv.lib.optionalString (!stdenv.is64bit) "-falign-functions=4"}";
 
   # TODO : make mod-check fails
   doCheck = false;
diff --git a/pkgs/development/interpreters/clisp/default.nix b/pkgs/development/interpreters/clisp/default.nix
index b8af3f6d7479..919c3771bc5d 100644
--- a/pkgs/development/interpreters/clisp/default.nix
+++ b/pkgs/development/interpreters/clisp/default.nix
@@ -53,7 +53,7 @@ stdenv.mkDerivation rec {
         clx/new-clx bindings/glibc pcre rawsock wildcard zlib
   '';
 
-  NIX_CFLAGS_COMPILE="-O0";
+  NIX_CFLAGS_COMPILE = "-O0 ${stdenv.lib.optionalString (!stdenv.is64bit) "-falign-functions=4"}";
 
   # TODO : make mod-check fails
   doCheck = false;