diff --git a/pkgs/development/libraries/gobject-introspection/absolute_shlib_path.patch b/pkgs/development/libraries/gobject-introspection/absolute_shlib_path.patch
index 04bcc42a032f..2803d767dc71 100644
--- a/pkgs/development/libraries/gobject-introspection/absolute_shlib_path.patch
+++ b/pkgs/development/libraries/gobject-introspection/absolute_shlib_path.patch
@@ -1,6 +1,40 @@
---- ./giscanner/utils.py.orig	2014-08-14 22:05:05.055334080 +0200
-+++ ./giscanner/utils.py	2014-08-14 22:05:24.687497334 +0200
-@@ -110,17 +110,11 @@
+diff --git a/giscanner/shlibs.py b/giscanner/shlibs.py
+index 838d343..9dbdc0f 100644
+--- a/giscanner/shlibs.py
++++ b/giscanner/shlibs.py
+@@ -53,10 +53,24 @@ def _resolve_libtool(options, binary, libraries):
+ # Match absolute paths on OS X to conform to how libraries are usually
+ # referenced on OS X systems.
+ def _ldd_library_pattern(library_name):
++    nix_store_dir = re.escape('@nixStoreDir@'.rstrip('/'))
+     pattern = "(?<![A-Za-z0-9_-])(lib*%s[^A-Za-z0-9_-][^\s\(\)]*)"
+-    if platform.system() == 'Darwin':
+-        pattern = "([^\s]*lib*%s[^A-Za-z0-9_-][^\s\(\)]*)"
+-    return re.compile(pattern % re.escape(library_name))
++    pattern = r'''
++        (
++          (?:
++            # First match Nix store paths because they need to be absolute.
++            (?:%s(?:/[^/]*)+)
++            # Everything else not a store path remains relative, because we
++            # would end up having absolute build paths in the resulting GIR
++            # file.
++            | (?<=/)
++          )
++          # And finally the library itself:
++          (?:lib%s[^A-Za-z0-9_-][^\s\(\)]*)
++        )
++    '''
++    return re.compile(pattern % (nix_store_dir, re.escape(library_name)),
++                      re.VERBOSE)
+ 
+ 
+ # This is a what we do for non-la files. We assume that we are on an
+diff --git a/giscanner/utils.py b/giscanner/utils.py
+index 660081e..c9c767a 100644
+--- a/giscanner/utils.py
++++ b/giscanner/utils.py
+@@ -109,17 +109,11 @@ def extract_libtool_shlib(la_file):
      if dlname is None:
          return None
  
diff --git a/pkgs/development/libraries/gobject-introspection/default.nix b/pkgs/development/libraries/gobject-introspection/default.nix
index f429e1dc6c36..c2f60d460d7e 100644
--- a/pkgs/development/libraries/gobject-introspection/default.nix
+++ b/pkgs/development/libraries/gobject-introspection/default.nix
@@ -1,5 +1,7 @@
 { stdenv, fetchurl, glib, flex, bison, pkgconfig, libffi, python
-, libintlOrEmpty, autoconf, automake, otool }:
+, libintlOrEmpty, autoconf, automake, otool
+, substituteAll, nixStoreDir ? "/nix/store"
+}:
 # now that gobjectIntrospection creates large .gir files (eg gtk3 case)
 # it may be worth thinking about using multiple derivation outputs
 # In that case its about 6MB which could be separated
@@ -33,7 +35,10 @@ stdenv.mkDerivation rec {
 
   setupHook = ./setup-hook.sh;
 
-  patches = [ ./absolute_shlib_path.patch ];
+  patches = stdenv.lib.singleton (substituteAll {
+    src = ./absolute_shlib_path.patch;
+    inherit nixStoreDir;
+  });
 
   meta = with stdenv.lib; {
     description = "A middleware layer between C libraries and language bindings";
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index a8f01dda21f0..b04d2c1457bc 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -6639,7 +6639,9 @@ let
   #GMP ex-satellite, so better keep it near gmp
   mpfr = callPackage ../development/libraries/mpfr/default.nix { };
 
-  gobjectIntrospection = callPackage ../development/libraries/gobject-introspection { };
+  gobjectIntrospection = callPackage ../development/libraries/gobject-introspection {
+    nixStoreDir = config.nix.storeDir or "/nix/store";
+  };
 
   goocanvas = callPackage ../development/libraries/goocanvas { };