diff --git a/pkgs/development/python-modules/libusb1/default.nix b/pkgs/development/python-modules/libusb1/default.nix
new file mode 100644
index 000000000000..adf1bc236183
--- /dev/null
+++ b/pkgs/development/python-modules/libusb1/default.nix
@@ -0,0 +1,26 @@
+{ stdenv, lib, buildPythonPackage, fetchPypi, libusb1 }:
+
+buildPythonPackage rec {
+  pname = "libusb1";
+  version = "1.6.4";
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "03b7xrz8vqg8w0za5r503jhcmbd1ls5610jcja1rqz833nf0v4wc";
+  };
+
+  postPatch = lib.optionalString stdenv.isLinux ''
+    substituteInPlace usb1/libusb1.py --replace \
+      "ctypes.util.find_library(base_name)" \
+      "'${libusb1}/lib/libusb${stdenv.hostPlatform.extensions.sharedLibrary}'"
+  '';
+
+  buildInputs = [ libusb1 ];
+
+  meta = with stdenv.lib; {
+    homepage    = https://github.com/vpelletier/python-libusb1;
+    description = "Python ctype-based wrapper around libusb1";
+    license     = licenses.lgpl2Plus;
+    maintainers = with maintainers; [ rnhmjoj ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 2f0bbdd9dc73..6047e1f83cd3 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4002,6 +4002,8 @@ in {
 
   libtmux = callPackage ../development/python-modules/libtmux { };
 
+  libusb1 = callPackage ../development/python-modules/libusb1 { inherit (pkgs) libusb1; };
+
   linuxfd = callPackage ../development/python-modules/linuxfd { };
 
   locket = buildPythonPackage rec {