diff --git a/pkgs/development/libraries/apr/default.nix b/pkgs/development/libraries/apr/default.nix
index 19adfb08cfa0..728ec87a1ce6 100644
--- a/pkgs/development/libraries/apr/default.nix
+++ b/pkgs/development/libraries/apr/default.nix
@@ -1,4 +1,4 @@
-{ lib, stdenv, fetchurl, fetchpatch, autoreconfHook }:
+{ lib, stdenv, fetchurl, fetchpatch, buildPackages, autoreconfHook }:
 
 stdenv.mkDerivation rec {
   pname = "apr";
@@ -17,6 +17,12 @@ stdenv.mkDerivation rec {
       # convince fetchpatch to restore missing `a/`, `b/` to paths
       extraPrefix = "";
     })
+
+    # Fix cross.
+    (fetchpatch {
+      url = "https://github.com/apache/apr/commit/866e1df66be6704a584feaf5c3d241e3d631d03a.patch";
+      sha256 = "0hhm5v5wx985c28dq6d9ngnyqihpsphq4mw7rwylk39k2p90ppcm";
+    })
   ] ++ lib.optionals stdenv.isDarwin [ ./is-this-a-compiler-bug.patch ];
 
   # This test needs the net
@@ -35,8 +41,8 @@ stdenv.mkDerivation rec {
   configureFlags = lib.optional (stdenv.hostPlatform != stdenv.buildPlatform) [
     "ac_cv_file__dev_zero=yes"
     "ac_cv_func_setpgrp_void=0"
-    "apr_cv_process_shared_works=1"
     "apr_cv_tcp_nodelay_with_cork=1"
+    "CC_FOR_BUILD=${buildPackages.stdenv.cc}/bin/cc"
   ] ++ lib.optionals (stdenv.hostPlatform.system == "i686-cygwin") [
     # Including the Windows headers breaks unistd.h.
     # Based on ftp://sourceware.org/pub/cygwin/release/libapr1/libapr1-1.3.8-2-src.tar.bz2
@@ -45,9 +51,9 @@ stdenv.mkDerivation rec {
 
   CPPFLAGS=lib.optionalString (stdenv.hostPlatform != stdenv.buildPlatform) "-DAPR_IOVEC_DEFINED";
 
-  nativeBuildInputs =
-    # Update libtool for macOS 11 support
-    lib.optional (stdenv.isDarwin && stdenv.isAarch64) [ autoreconfHook ];
+  # - Update libtool for macOS 11 support
+  # - Regenerate for cross fix patch
+  nativeBuildInputs = [ autoreconfHook ];
 
   enableParallelBuilding = true;
 
diff --git a/pkgs/top-level/all-packages.nix b/pkgs/top-level/all-packages.nix
index de9cffab1173..6b45f107734e 100644
--- a/pkgs/top-level/all-packages.nix
+++ b/pkgs/top-level/all-packages.nix
@@ -15534,7 +15534,9 @@ with pkgs;
 
   appstream-glib = callPackage ../development/libraries/appstream-glib { };
 
-  apr = callPackage ../development/libraries/apr { };
+  apr = callPackage ../development/libraries/apr {
+    autoreconfHook = buildPackages.autoreconfHook269;
+  };
 
   aprutil = callPackage ../development/libraries/apr-util {
     db = if stdenv.isFreeBSD then db4 else db;