diff --git a/pkgs/development/python-modules/guppy3/default.nix b/pkgs/development/python-modules/guppy3/default.nix
new file mode 100644
index 000000000000..578f979914cb
--- /dev/null
+++ b/pkgs/development/python-modules/guppy3/default.nix
@@ -0,0 +1,32 @@
+{ lib
+, buildPythonPackage
+, fetchFromGitHub
+, pythonOlder
+, tkinter
+}:
+
+buildPythonPackage rec {
+  pname = "guppy3";
+  version = "3.1.0";
+  disabled = pythonOlder "3.6";
+
+  src = fetchFromGitHub {
+    owner = "zhuyifei1999";
+    repo = pname;
+    rev = "v${version}";
+    sha256 = "0yjsn8najbic4f50nj6jzhzrhj1bw6918w0gihdkzhqynwgqi64m";
+  };
+
+  propagatedBuildInputs = [ tkinter ];
+
+  # Tests are starting a Tkinter GUI
+  doCheck = false;
+  pythonImportsCheck = [ "guppy" ];
+
+  meta = with lib; {
+    description = "Python Programming Environment & Heap analysis toolset";
+    homepage = "https://zhuyifei1999.github.io/guppy3/";
+    license = with licenses; [ mit ];
+    maintainers = with maintainers; [ fab ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 17f6624c42ea..1468786383f3 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -2854,6 +2854,8 @@ in {
   else
     callPackage ../development/python-modules/gunicorn { };
 
+  guppy3 = callPackage ../development/python-modules/guppy3 { };
+
   gurobipy = if stdenv.hostPlatform.system == "x86_64-darwin" then
     callPackage ../development/python-modules/gurobipy/darwin.nix { inherit (pkgs.darwin) cctools insert_dylib; }
   else if stdenv.hostPlatform.system == "x86_64-linux" then