diff --git a/pkgs/development/libraries/boost/darwin-no-system-python.patch b/pkgs/development/libraries/boost/darwin-no-system-python.patch
new file mode 100644
index 000000000000..73e0910336a1
--- /dev/null
+++ b/pkgs/development/libraries/boost/darwin-no-system-python.patch
@@ -0,0 +1,45 @@
+diff --git a/tools/build/src/tools/python.jam b/tools/build/src/tools/python.jam
+index 273b28a..2d2031e 100644
+--- a/tools/build/src/tools/python.jam
++++ b/tools/build/src/tools/python.jam
+@@ -428,13 +428,7 @@ local rule windows-installed-pythons ( version ? )
+ 
+ local rule darwin-installed-pythons ( version ? )
+ {
+-    version ?= $(.version-countdown) ;
+-
+-    local prefix
+-      = [ GLOB /System/Library/Frameworks /Library/Frameworks
+-          : Python.framework ] ;
+-
+-    return $(prefix)/Versions/$(version)/bin/python ;
++    return ;
+ }
+ 
+ 
+@@ -890,25 +884,6 @@ local rule configure ( version ? : cmd-or-prefix ? : includes * : libraries ? :
+ 
+     # See if we can find a framework directory on darwin.
+     local framework-directory ;
+-    if $(target-os) = darwin
+-    {
+-        # Search upward for the framework directory.
+-        local framework-directory = $(libraries[-1]) ;
+-        while $(framework-directory:D=) && $(framework-directory:D=) != Python.framework
+-        {
+-            framework-directory = $(framework-directory:D) ;
+-        }
+-
+-        if $(framework-directory:D=) = Python.framework
+-        {
+-            debug-message framework directory is \"$(framework-directory)\" ;
+-        }
+-        else
+-        {
+-            debug-message "no framework directory found; using library path" ;
+-            framework-directory = ;
+-        }
+-    }
+ 
+     local dll-path = $(libraries) ;
+ 
diff --git a/pkgs/development/libraries/boost/generic.nix b/pkgs/development/libraries/boost/generic.nix
index 34e837f7cd2b..dab6fac6f0cc 100644
--- a/pkgs/development/libraries/boost/generic.nix
+++ b/pkgs/development/libraries/boost/generic.nix
@@ -87,11 +87,13 @@ stdenv.mkDerivation {
   inherit src;
 
   patchFlags = optionalString (hostPlatform.libc == "msvcrt") "-p0";
-  patches = patches ++ optional (hostPlatform.libc == "msvcrt") (fetchurl {
-    url = "https://svn.boost.org/trac/boost/raw-attachment/tickaet/7262/"
-        + "boost-mingw.patch";
-    sha256 = "0s32kwll66k50w6r5np1y5g907b7lcpsjhfgr7rsw7q5syhzddyj";
-  });
+  patches = patches
+    ++ optional stdenv.isDarwin ./darwin-no-system-python.patch
+    ++ optional (hostPlatform.libc == "msvcrt") (fetchurl {
+      url = "https://svn.boost.org/trac/boost/raw-attachment/tickaet/7262/"
+          + "boost-mingw.patch";
+      sha256 = "0s32kwll66k50w6r5np1y5g907b7lcpsjhfgr7rsw7q5syhzddyj";
+    });
 
   meta = {
     homepage = http://boost.org/;