diff --git a/pkgs/development/python-modules/pyregion/default.nix b/pkgs/development/python-modules/pyregion/default.nix
new file mode 100644
index 000000000000..dda3a3cd161a
--- /dev/null
+++ b/pkgs/development/python-modules/pyregion/default.nix
@@ -0,0 +1,34 @@
+{ lib
+, buildPythonPackage
+, fetchPypi
+, pyparsing
+, numpy
+, cython
+, astropy
+}:
+
+buildPythonPackage rec {
+  pname = "pyregion";
+  version = "2.0";
+
+  doCheck = false; # tests require pytest-astropy
+
+  src = fetchPypi {
+    inherit pname version;
+    sha256 = "a8ac5f764b53ec332f6bc43f6f2193ca13e8b7d5a3fb2e20ced6b2ea42a9d094";
+  };
+
+  propagatedBuildInputs = [
+    pyparsing
+    numpy
+    cython
+    astropy
+  ];
+
+  meta = with lib; {
+    description = "Python parser for ds9 region files";
+    homepage = https://github.com/astropy/pyregion;
+    license = licenses.mit;
+    maintainers = [ maintainers.smaret ];
+  };
+}
diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index cf385dc3c8ec..d778e43de06c 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -4965,6 +4965,8 @@ in {
 
   potr = callPackage ../development/python-modules/potr {};
 
+  pyregion = callPackage ../development/python-modules/pyregion {};
+
   python-u2flib-host = callPackage ../development/python-modules/python-u2flib-host { };
 
   pluggy = callPackage ../development/python-modules/pluggy {};