diff --git a/pkgs/applications/graphics/darktable/default.nix b/pkgs/applications/graphics/darktable/default.nix
index ac44a1e875c0..51a401d4b8c8 100644
--- a/pkgs/applications/graphics/darktable/default.nix
+++ b/pkgs/applications/graphics/darktable/default.nix
@@ -3,7 +3,7 @@
 , ilmbase, gtk3, intltool, lcms2, lensfun, libX11, libexif, libgphoto2, libjpeg
 , libpng, librsvg, libtiff, openexr, osm-gps-map, pkgconfig, sqlite, libxslt
 , openjpeg, lua, pugixml, colord, colord-gtk, libwebp, libsecret, gnome3
-, ocl-icd
+, ocl-icd, pcre, gtk-mac-integration
 }:
 
 stdenv.mkDerivation rec {
@@ -18,24 +18,32 @@ stdenv.mkDerivation rec {
   nativeBuildInputs = [ cmake ninja llvm pkgconfig intltool perl desktop-file-utils wrapGAppsHook ];
 
   buildInputs = [
-    cairo curl exiv2 glib gtk3 ilmbase lcms2 lensfun libX11 libexif
+    cairo curl exiv2 glib gtk3 ilmbase lcms2 lensfun libexif
     libgphoto2 libjpeg libpng librsvg libtiff openexr sqlite libxslt
     libsoup graphicsmagick json-glib openjpeg lua pugixml
-    colord colord-gtk libwebp libsecret gnome3.adwaita-icon-theme
-    osm-gps-map ocl-icd
-  ];
-    
+    libwebp libsecret gnome3.adwaita-icon-theme osm-gps-map pcre
+  ] ++ stdenv.lib.optionals stdenv.isLinux [
+    colord colord-gtk libX11 ocl-icd
+  ] ++ stdenv.lib.optional stdenv.isDarwin gtk-mac-integration;
+
   cmakeFlags = [
     "-DBUILD_USERMANUAL=False"
+  ] ++ stdenv.lib.optionals stdenv.isDarwin [
+    "-DUSE_COLORD=OFF"
+    "-DUSE_KWALLET=OFF"
   ];
 
+
   # darktable changed its rpath handling in commit
   # 83c70b876af6484506901e6b381304ae0d073d3c and as a result the
   # binaries can't find libdarktable.so, so change LD_LIBRARY_PATH in
   # the wrappers:
-  preFixup = ''
+  preFixup = let
+    libPathEnvVar = if stdenv.isDarwin then "DYLD_LIBRARY_PATH" else "LD_LIBRARY_PATH";
+    libPathPrefix = "$out/lib/darktable" + stdenv.lib.optionalString stdenv.isLinux ":${ocl-icd}/lib";
+  in ''
     gappsWrapperArgs+=(
-      --prefix LD_LIBRARY_PATH ":" "$out/lib/darktable:${ocl-icd}/lib"
+      --prefix ${libPathEnvVar} ":" "${libPathPrefix}"
     )
   '';
 
@@ -43,7 +51,7 @@ stdenv.mkDerivation rec {
     description = "Virtual lighttable and darkroom for photographers";
     homepage = https://www.darktable.org;
     license = licenses.gpl3Plus;
-    platforms = platforms.linux;
+    platforms = platforms.linux ++ platforms.darwin;
     maintainers = with maintainers; [ goibhniu rickynils flosse mrVanDalo ];
   };
 }