diff --git a/pkgs/development/interpreters/python/cpython/2.7/cross-compile.patch b/pkgs/development/interpreters/python/cpython/2.7/cross-compile.patch
deleted file mode 100644
index 4d0c72675cc4..000000000000
--- a/pkgs/development/interpreters/python/cpython/2.7/cross-compile.patch
+++ /dev/null
@@ -1,44 +0,0 @@
-commit 9ac1104b075ecea6175e2214b81c6538adbb9e84
-Author: Ben Gamari <ben@smart-cactus.org>
-Date:   Tue Oct 17 23:53:25 2017 -0400
-
-    Fix it
-
-diff --git a/Makefile.pre.in b/Makefile.pre.in
-index e288964..ddc7428 100644
---- a/Makefile.pre.in
-+++ b/Makefile.pre.in
-@@ -1120,27 +1120,27 @@ libinstall:	build_all $(srcdir)/Lib/$(PLATDIR) $(srcdir)/Modules/xxmodule.c
- 		$(INSTALL_DATA) $(srcdir)/Modules/xxmodule.c \
- 			$(DESTDIR)$(LIBDEST)/distutils/tests ; \
- 	fi
--	PYTHONPATH=$(DESTDIR)$(LIBDEST)  $(RUNSHARED) \
-+	$(RUNSHARED) \
- 		$(PYTHON_FOR_BUILD) -Wi -tt $(DESTDIR)$(LIBDEST)/compileall.py \
- 		-d $(LIBDEST) -f \
- 		-x 'bad_coding|badsyntax|site-packages|lib2to3/tests/data' \
- 		$(DESTDIR)$(LIBDEST)
--	PYTHONPATH=$(DESTDIR)$(LIBDEST) $(RUNSHARED) \
-+	$(RUNSHARED) \
- 		$(PYTHON_FOR_BUILD) -Wi -tt -O $(DESTDIR)$(LIBDEST)/compileall.py \
- 		-d $(LIBDEST) -f \
- 		-x 'bad_coding|badsyntax|site-packages|lib2to3/tests/data' \
- 		$(DESTDIR)$(LIBDEST)
--	-PYTHONPATH=$(DESTDIR)$(LIBDEST)  $(RUNSHARED) \
-+	-$(RUNSHARED) \
- 		$(PYTHON_FOR_BUILD) -Wi -t $(DESTDIR)$(LIBDEST)/compileall.py \
- 		-d $(LIBDEST)/site-packages -f \
- 		-x badsyntax $(DESTDIR)$(LIBDEST)/site-packages
--	-PYTHONPATH=$(DESTDIR)$(LIBDEST) $(RUNSHARED) \
-+	-$(RUNSHARED) \
- 		$(PYTHON_FOR_BUILD) -Wi -t -O $(DESTDIR)$(LIBDEST)/compileall.py \
- 		-d $(LIBDEST)/site-packages -f \
- 		-x badsyntax $(DESTDIR)$(LIBDEST)/site-packages
--	-PYTHONPATH=$(DESTDIR)$(LIBDEST) $(RUNSHARED) \
-+	-$(RUNSHARED) \
- 		$(PYTHON_FOR_BUILD) -m lib2to3.pgen2.driver $(DESTDIR)$(LIBDEST)/lib2to3/Grammar.txt
--	-PYTHONPATH=$(DESTDIR)$(LIBDEST) $(RUNSHARED) \
-+	-$(RUNSHARED) \
- 		$(PYTHON_FOR_BUILD) -m lib2to3.pgen2.driver $(DESTDIR)$(LIBDEST)/lib2to3/PatternGrammar.txt
- 
- # Create the PLATDIR source directory, if one wasn't distributed..
diff --git a/pkgs/development/interpreters/python/cpython/2.7/default.nix b/pkgs/development/interpreters/python/cpython/2.7/default.nix
index 28ad3aeca918..61f17a959bd9 100644
--- a/pkgs/development/interpreters/python/cpython/2.7/default.nix
+++ b/pkgs/development/interpreters/python/cpython/2.7/default.nix
@@ -88,11 +88,6 @@ let
       # only works for GCC and Apple Clang. This makes distutils to call C++
       # compiler when needed.
       ./python-2.7-distutils-C++.patch
-
-    ] ++ [
-
-      # Don't use pass host PYTHONPATH to build python
-      #./cross-compile.patch
     ];
 
   preConfigure = ''