diff --git a/pkgs/top-level/python-packages.nix b/pkgs/top-level/python-packages.nix
index 4d9ebdca2e50..8df763844c0d 100644
--- a/pkgs/top-level/python-packages.nix
+++ b/pkgs/top-level/python-packages.nix
@@ -26101,6 +26101,13 @@ in {
 
     propagatedBuildInputs = with self; [ zope_interface ];
 
+    # Patch t.p._inotify to point to libc. Without this,
+    # twisted.python.runtime.platform.supportsINotify() == False
+    patchPhase = optionalString stdenv.isLinux ''
+      substituteInPlace twisted/python/_inotify.py --replace \
+        "ctypes.util.find_library('c')" "'${stdenv.glibc.out}/lib/libc.so.6'"
+    '';
+
     # Generate Twisted's plug-in cache.  Twisted users must do it as well.  See
     # http://twistedmatrix.com/documents/current/core/howto/plugin.html#auto3
     # and http://bugs.debian.org/cgi-bin/bugreport.cgi?bug=477103 for